F. Jon Kull

Academic Appointments

Rodgers Professor of Chemistry
Dean of the Guarini School of Graduate and Advanced Studies

F. Jon Kull '88 is Dean of the Guarini School of Graduate and Advanced Studies at Dartmouth College and the inaugural holder of the Rodgers Professorship at Dartmouth College.

An internationally known structural biologist and biochemist, Kull joined Dartmouth's chemistry faculty in 2001. His research in structural biology and biophysics focuses on the mechanism of molecular motor proteins and the proteins involved in the regulation of bacterial virulence. Kull teaches undergraduate chemistry, biochemistry, and biophysical chemistry, and has supervised graduate students in the Department of Chemistry and the Molecular and Cellular Biology programs. In 2010, he was awarded the Dean of the Faculty Award for Outstanding Mentoring and Advising. In 2012 he was named a DCAL Faculty Fellow by the Dartmouth Center for the Advancement of Learning for his efforts in leading a monthly Teaching Science Seminar, as well as his work in "flipping" his general chemistry class.

Kull returned to Dartmouth as an assistant professor in 2001, was promoted to associate professor in 2007, and to full professor in 2012. In 2012, Kull was appointed to the Rodgers Professorship at Dartmouth College, a new faculty chair endowed by former trustee T.J. Rodgers '70 and appointed as Graduate Dean. He was recently reappointed as Dean of the Guarini School.

Kull has published his work in a number of high-profile journals, including Nature, Cell, Nature Structural and Molecular Biology, and the Proceedings of the National Academy of Sciences. He has served as an editorial board member for the Journal of Biological Chemistry and as a standing member of the NIH's Bacterial Pathogenesis Study Section.

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Contact

F.Jon.Kull@dartmouth.edu

603-646-1552

Burke, Room 304

HB 6128

Education

A.B. Dartmouth College
Ph.D. University of California at San Francisco

Selected Publications

Markham LE, Tolbert JD, Kull FJ, Midgett, CR, Micalizio GC. (2021) An enantiodefined conformationally constrained fatty acid mimetic and potent inhibitor of ToxT. ACS Medicinal Chemistry Letters. 2021, 12, 9, 1493-1497.
Midgett CR, Talbot KM, Day JL, Munson GP, Kull FJ. (2021) Structure of the master regulator Rns reveals an inhibitor of enterotoxigenic Escherichia coli virulence regulons. Sci Rep. 2021 Aug 2;11(1):15663. doi: 10.1038/s41598-021-95123-2. PubMed PMID: 34341412; PubMed Central PMCID: PMC8329261.
Midgett CR, Swindell RA, Pellegrini M, Kull FJ. (2020) A disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts. Sci Rep. 2020 Jun 2;10(1):9002. PubMed PMID: 32488093; PubMed Central PMCID: PMC7265457.
Cruite JT, Kovacikova G, Clark KA, Woodbrey AK, Skorupski K, Kull FJ. (2019) Structural basis for virulence regulation in Vibrio cholerae by unsaturated fatty acid components of bile. Communications Biology, volume 2, Article number: 440.

Woodbrey AK, Onyango EO, Kovacikova G, Kull FJ, Gribble GW. (2018) A Modified ToxT Inhibitor Reduces Vibrio choleraeVirulence in Vivo. Biochemistry. 2018 Sep 25;57(38):5609-5615.
Cruite J, Succo P, Raychaudhuri S, Kull FJ. (2018) Crystal structure of an inactive variant of the quorum-sensing master regulator HapR from the protease-deficient non-O1, non-O139 Vibrio cholerae strain V2. Acta Crystallogr F Struct Biol Commun. Jun 1;74(Pt 6):331-336 Epub 2018 May 17. PMID: 29870016

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F. Jon Kull

Rodgers Professor of Chemistry

Dean of the Guarini School of Graduate and Advanced Studies

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F. Jon Kull

Rodgers Professor of Chemistry

Dean of the Guarini School of Graduate and Advanced Studies

Contact

Education

Selected Publications

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